PBK

Pseudophakic Bullous Keratopathy (PBK) Treatment In Jaipur At Pink City Eye & Retina Center

At Pink City Eye & Retina Center in Jaipur, we are committed to providing comprehensive care for every stage of your eye health journey — including potential complications that may arise after eye surgeries. One such condition is Pseudophakic Bullous Keratopathy (PBK), a corneal disorder that may occur as a delayed complication following cataract surgery, especially in cases involving intraocular lens (IOL) implantation. Though uncommon, PBK can cause considerable discomfort and vision issues, and early diagnosis is critical for effective Pseudophakic Bullous Keratopathy (PBK) Treatment in Jaipur.

What is Pseudophakic Bullous Keratopathy (PBK)?

Our eye’s cornea is composed of several layers. The innermost layer is called the endothelium. Endothelial cells are crucial for maintaining the cornea’s clarity and health, as they continuously pump excess fluid out of the cornea.

PBK occurs when these endothelial cells are damaged during or after cataract surgery. When these cells are reduced in number or unable to function properly, fluid starts to accumulate in the cornea, leading to swelling (edema). Over time, this swelling can worsen, causing small, fluid-filled blisters (bullae) to form on the corneal surface. When these blisters rupture, they can cause pain and further impair vision.

Causes of Pseudophakic Bullous Keratopathy (PBK)

PBK mainly results from damage to the innermost layer of the cornea — the endothelium — which is essential for keeping the cornea clear and healthy. The following are the most common causes:

  • Surgical Trauma: The most common cause of PBK is injury to the corneal endothelial cells during cataract surgery, particularly if the procedure is complex or prolonged.

  • Pre-existing Corneal Conditions: Patients with conditions like Fuchs’ endothelial dystrophy already have weak endothelial cells, increasing their risk of developing PBK after surgery.

  • Malpositioned or Old-Design IOLs: Improper placement or older designs of intraocular lenses can rub against the corneal endothelium, causing long-term damage.

  • Excess Surgical Energy: Use of high ultrasound energy (phacoemulsification) during surgery can generate heat and shock waves that harm endothelial cells.

  • Post-Surgical Inflammation or Infection: Chronic inflammation or postoperative infections can lead to further endothelial damage.

  • Secondary Glaucoma: Increased eye pressure after surgery puts stress on the endothelium, accelerating cell loss.

  • Previous Eye Surgeries or Trauma: A history of multiple intraocular surgeries or physical injury to the eye can increase the likelihood of endothelial failure.

  • Systemic Risk Factors: Conditions like aging, diabetes, or autoimmune diseases may impair healing and endothelial cell function, making the cornea more vulnerable.

Symptoms of Pseudophakic Bullous Keratopathy (PBK)

PBK symptoms often begin gradually but can significantly impact your daily comfort and vision. Here’s what patients commonly experience:

Blurred or Hazy Vision

Most noticeable in the morning, as the cornea tends to retain more fluid overnight.

Eye Pain or Discomfort

Pain may occur due to ruptured blisters (bullae) on the corneal surface, exposing sensitive nerve endings.

Light Sensitivity (Photophobia)

Bright lights can cause discomfort or pain due to corneal swelling and irregularities.

Foreign Body Sensation

A gritty or sandy feeling, like something is stuck in the eye, caused by surface irregularities.

Excessive Tearing

The eye often becomes watery in response to irritation from bullae or edema.

Halos and Glare

Patients might perceive rainbow-hued rings around light sources, particularly at night, due to light dispersion through the swollen cornea.

Reduced Night Vision and Contrast Sensitivity

Driving at night or seeing in dim lighting may become more difficult.

Progressive Vision Loss

In advanced stages, vision can decline significantly and may not improve with glasses or contact lenses.

If you notice any of these symptoms, especially following cataract surgery, we encourage you to consult our experienced eye specialists at Pink City Eye & Retina Center, Jaipur. Early diagnosis and management can protect your vision and reduce discomfort.

How is Pseudophakic Bullous Keratopathy (PBK) Diagnosed in Jaipur At Pink City Eye & Retina Center, Jaipur

At Pink City Eye & Retina Center in Jaipur, accurate diagnosis is the first and most essential step toward managing any eye condition — especially complex post-surgical issues like Pseudophakic Bullous Keratopathy (PBK). Since PBK can mimic other corneal disorders, we use a combination of advanced diagnostic tools and expert clinical assessment to confirm the condition and evaluate its severity.

Here’s how we diagnose PBK in a comprehensive and patient-focused manner as part of our approach to Pseudophakic Bullous Keratopathy (PBK) Treatment in Jaipur:

1. Slit-Lamp Examination

This is often the first step in evaluation. Using a specialized microscope with high-intensity light, we examine:

  • Corneal clarity and swelling (edema)

  • Presence of bullae (fluid-filled blisters)

  • Intraocular lens (IOL) positioning

  • Signs of inflammation or infection

This allows us to visually assess the health of your cornea and identify hallmark signs of PBK.

2. Corneal Pachymetry

Pachymetry is a technique utilized for measuring the thickness of your cornea. In PBK, the cornea often becomes abnormally thick due to fluid retention. This test helps us:

  • Quantify corneal edema

  • Track disease progression over time

  • Evaluate the need for medical or surgical intervention

3. Specular Microscopy

This non-invasive imaging test evaluates the endothelial layer of the cornea — the layer most affected in PBK. It provides:

  • Cell count and density

  • Cell shape and size variation

  • Insight into extent of endothelial damage

Low endothelial cell counts confirm the diagnosis of PBK and help determine treatment urgency.

4. Anterior Segment OCT (Optical Coherence Tomography)

AS-OCT is a cutting-edge imaging method that gives high-resolution cross-sectional images of the cornea. It is especially useful to:

  • Visualize corneal layers in detail

  • Assess the extent of stromal and epithelial edema

  • Monitor IOL positioning and corneal interface

  1. Intraocular Pressure (IOP) Measurement

Since secondary glaucoma can coexist with or worsen PBK, measuring eye pressure is essential to rule it out or treat it alongside PBK.

6. Visual Acuity Testing

This standard eye test helps us understand the extent of vision loss caused by PBK and to monitor how treatment improves visual outcomes.

7. Dilated Fundus Examination

To ensure a thorough diagnosis, we also examine the retina and optic nerve to rule out any other underlying causes of vision problems, such as macular degeneration or optic neuropathy.

Treatment Options for Pseudophakic Bullous Keratopathy (PBK) In Jaipur At Pink City Eye & Retina Center

At Pink City Eye & Retina Center, Jaipur, we understand that managing Pseudophakic Bullous Keratopathy (PBK) requires a customized approach based on the stage and severity of the condition. Whether it’s relieving discomfort in early cases or restoring vision through advanced surgical techniques in more severe ones, our goal is to provide safe, effective, and compassionate care at every step as part of our specialized Pseudophakic Bullous Keratopathy (PBK) Treatment in Jaipur.

1. Medical (Non-Surgical) Management – For Early or Mild PBK

In the early stages of PBK, where symptoms are mild and vision is still relatively preserved, we often start with non-surgical treatments to manage symptoms and delay disease progression:

🔹 Hypertonic Saline Drops or Ointments (5% NaCl)

These agents draw out surplus fluid from the cornea, assisting in the reduction of swelling and enhancing corneal clarity.

🔹 Bandage Contact Lenses (BCL)

Special soft lenses that protect the corneal surface and relieve pain caused by ruptured bullae.

🔹 Lubricating & Anti-inflammatory Eye Drops

Artificial tears keep the eyes comfortable, while topical steroids may be used (with caution) to reduce inflammation.

🔹 Intraocular Pressure (IOP) Control

If PBK is associated with secondary glaucoma, medications may be prescribed to lower eye pressure and protect the remaining endothelial cells.

🔹 Monitoring and Follow-Up

Regular monitoring of corneal thickness, vision changes, and endothelial health is essential during this phase.

2. Surgical Management – For Advanced PBK

When conservative measures fail or vision loss becomes significant, surgical intervention is often necessary to restore corneal function and improve visual outcomes. At Pink City Eye & Retina Center, we offer the most advanced surgical solutions, including:

🔹 Endothelial Keratoplasty (DSEK/DSAEK & DMEK)

These are minimally invasive corneal transplantation procedures that exclusively target the compromised endothelial layer, preserving the healthy outer corneal layers.

  • DSEK/DSAEK: Transplants a thin layer of donor tissue, including endothelium and a bit of stroma. Offers faster healing and visual recovery than full-thickness grafts.

  • DMEK: Transplants only Descemet’s membrane and endothelium, providing even better visual outcomes and lower rejection risk.

These are the most preferred surgical treatments for PBK today.

🔹 Penetrating Keratoplasty (PK) – Full-Thickness Corneal Transplant

Recommended in cases where corneal damage is extensive or other layers are also affected.

  • A diseased cornea is wholly substituted with healthy, compatible donor tissue.

  • Recovery takes longer and requires more post-operative care, but it’s effective in severe or complicated PBK cases.

🔹 Intraocular Lens (IOL) Repositioning or Exchange

If a poorly positioned or outdated IOL is contributing to endothelial damage:

  • The lens may be repositioned, removed, or replaced with a safer, posterior chamber or scleral-fixated IOL.

  • Often performed alongside corneal transplant surgery for best results.

🔹 Amniotic Membrane Transplantation

In patients with severe pain due to persistent bullae, amniotic membrane grafts may be applied to the eye surface to:

  • Promote healing

  • Reduce discomfort

  • Serve as a temporary solution before corneal transplant

🔹 Conjunctival Flap or Tarsorrhaphy (Protective Surgery)

In very rare cases where visual recovery is unlikely but pain is severe:

  • A conjunctival flap or partial eyelid closure may be done to protect the eye and relieve pain, especially in eyes with poor visual potential.

Conclusion

 If you or a loved one are experiencing symptoms of corneal discomfort or vision loss after cataract surgery, timely evaluation is crucial. At Pink City Eye & Retina Center, we are committed to providing advanced and personalized Pseudophakic Bullous Keratopathy (PBK) Treatment in Jaipur. With expert care and cutting-edge technology, our Jaipur-based team strives to restore vision and improve quality of life. Don’t let PBK compromise your sight—trust the specialists in Pseudophakic Bullous Keratopathy (PBK) Treatment in Jaipur for effective and compassionate eye care.

Frequently Asked Questions (FAQs)

PBK can cause long-term corneal damage if left untreated. However, with timely and appropriate surgical care, we can often restore much of the lost vision and improve comfort significantly.

When the root cause — such as a misaligned intraocular lens — is addressed during treatment, recurrence is rare. However, regular follow-up is important to monitor the health of the cornea over time

Not at all. At Pink City Eye & Retina Center, corneal transplant procedures are typically done under local or topical anesthesia, ensuring a painless experience with minimal post-operative discomfort.

Yes, in many cases. Careful surgical technique during cataract surgery and identifying patients at higher risk (like those with Fuchs’ dystrophy) can reduce the chances of developing PBK.

If ignored, PBK can progress to severe vision loss. But with proper treatment — especially corneal transplantation — we can often restore useful vision and prevent further deterioration.

Unfortunately, no. PBK requires medical or surgical intervention. Supportive care may offer temporary alleviation, but without intervention, the condition typically deteriorates.

Post-operative care is crucial. We advise patients to:

  • Avoid rubbing or touching the eye

  • Use all prescribed medications as directed

  • Attend all follow-up appointments

  • Protect the eye from injury or dust

These steps help promote healing and reduce the risk of complications.

Yes, PBK can appear even years after surgery, especially if the endothelial layer was weakened during the original procedure. This is why long-term monitoring is important, especially in high-risk individuals.

 If you’re looking for the best doctor for PBK (Pseudophakic Bullous Keratopathy) treatment in Jaipur, Dr. Abhishek Kothari at Pink City Eye & Retina Center is highly recommended. He provides specialized care for corneal complications following cataract surgery.

 The cost of PBK treatment varies depending on the severity and whether a corneal transplant or medical therapy is needed. At Pink City Eye & Retina Center, Jaipur, we ensure affordable care with transparent pricing.

 Appointments for PBK treatment can be booked by contacting Pink City Eye & Retina Center, Jaipur at 0141-4901083, emailing [email protected], or visiting the clinic during working hours: Monday to Saturday, 10:00 AM – 7:00 PM, and Sunday, 10:00 AM – 1:00 PM.

 For PBK treatment in Jaipur, Pink City Eye & Retina Center is a leading choice. We offer expert diagnosis and treatment, including corneal care and surgical management when needed.

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